Serotonin and neurotensin inputs in the vCA1 dictate opposing social valence

Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08809-2Aversive and rewarding social experiences are linked to conspecific identity through converging dorsal raphe 5-HT and paraventricular nucleus of the thalamus neurotensin signals in the vCA1 that instruct opposing valence, representing a synaptic switch for flexible social valence computation.

Apr 30, 2025 - 18:23
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Serotonin and neurotensin inputs in the vCA1 dictate opposing social valence

Nature, Published online: 30 April 2025; doi:10.1038/s41586-025-08809-2Aversive and rewarding social experiences are linked to conspecific identity through converging dorsal raphe 5-HT and paraventricular nucleus of the thalamus neurotensin signals in the vCA1 that instruct opposing valence, representing a synaptic switch for flexible social valence computation.