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Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3

Nature, Published online: 26 March 2025; doi:10.1038/s41586-025-08795-5The RBPJ–NCOR repressor complex is identified as a negative regulator of FOXP3 expression through modulation of histone acetylation in induced regulatory T cells.

Mar 27, 2025 - 07:07
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Genome-wide CRISPR screen in human T cells reveals regulators of FOXP3

Nature, Published online: 26 March 2025; doi:10.1038/s41586-025-08795-5The RBPJ–NCOR repressor complex is identified as a negative regulator of FOXP3 expression through modulation of histone acetylation in induced regulatory T cells.

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