Opening odds for the 2025 men’s Sweet 16
Gregory Fisher-Imagn Images The NCAA tournament is wrapping up the first week and the Sweet 16 field is settling. We have the opening point spreads, totals, and moneyline odds for next week’s third round. The 2025 NCAA men’s basketball tournament is working its way through the second round and the heavyweights are advancing to the Sweet 16. The tournament has not featured much of the usual drama, but it also means we’re getting some big programs headed into the second weekend. Maybe we’ll see some drama next weekend. As each matchup is settled, we’ll be providing the opening odds courtesy of FanDuel Sportsbook. The lines will change, and so these will simply be the odds from when they first open. Keep an eye out because the lines will change for each game, with some more drastic than others. South region TBD vs. #5 Michigan TBD vs. TBD East region TBD vs. TBD TBD vs. TBD Midwest region TBD vs. #4 Purdue TBD vs. TBD West region TBD vs. TBD #3 Texas Tech vs. #10 Arkansas Point spread: Texas Tech -4.5Total: 144.5Moneyline: Texas Tech -218, Arkansas +180


The NCAA tournament is wrapping up the first week and the Sweet 16 field is settling. We have the opening point spreads, totals, and moneyline odds for next week’s third round.
The 2025 NCAA men’s basketball tournament is working its way through the second round and the heavyweights are advancing to the Sweet 16. The tournament has not featured much of the usual drama, but it also means we’re getting some big programs headed into the second weekend. Maybe we’ll see some drama next weekend.
As each matchup is settled, we’ll be providing the opening odds courtesy of FanDuel Sportsbook. The lines will change, and so these will simply be the odds from when they first open. Keep an eye out because the lines will change for each game, with some more drastic than others.
South region
TBD vs. #5 Michigan
TBD vs. TBD
East region
TBD vs. TBD
TBD vs. TBD
Midwest region
TBD vs. #4 Purdue
TBD vs. TBD
West region
TBD vs. TBD
#3 Texas Tech vs. #10 Arkansas
Point spread: Texas Tech -4.5
Total: 144.5
Moneyline: Texas Tech -218, Arkansas +180