Deep Visual Proteomics maps proteotoxicity in a genetic liver disease
Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08885-4High-resolution spatial proteomics were used to map molecular events during hepatocyte stress in pseudotime across all fibrosis stages, recapitulating known disease progression markers and revealing early peroxisomal activation and late-stage proteotoxic phenotypes.
Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08885-4High-resolution spatial proteomics were used to map molecular events during hepatocyte stress in pseudotime across all fibrosis stages, recapitulating known disease progression markers and revealing early peroxisomal activation and late-stage proteotoxic phenotypes.
