Timing and trajectory of <i>BCR::ABL1-</i>driven chronic myeloid leukaemia

Nature, Published online: 09 April 2025; doi:10.1038/s41586-025-08817-2Explosive growth is attributed to the BCR::ABL1 gene 3–14 years before diagnosis of chronic myeloid leukaemia, highlighting the oncogenic potency of gene fusion and the slow and sequential trajectories of most other cancers.

Apr 9, 2025 - 18:11
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Timing and trajectory of <i>BCR::ABL1-</i>driven chronic myeloid leukaemia

Nature, Published online: 09 April 2025; doi:10.1038/s41586-025-08817-2Explosive growth is attributed to the BCR::ABL1 gene 3–14 years before diagnosis of chronic myeloid leukaemia, highlighting the oncogenic potency of gene fusion and the slow and sequential trajectories of most other cancers.