_Gang_Liu_Alamy.jpg?width=1280&auto=webp&quality=80&disable=upscale#)
_KristofferTripplaar_Alamy_.jpg?width=1280&auto=webp&quality=80&disable=upscale#)
STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity
Nature, Published online: 14 May 2025; doi:10.1038/s41586-025-09000-3Immune checkpoint blockade activates T cell immunity by reprogramming the STAT3 and STAT5 transcriptional pathways in dendritic cells, and STAT3 degradation is effective for treating tumours of multiple cancer types in mouse models.
Nature, Published online: 14 May 2025; doi:10.1038/s41586-025-09000-3Immune checkpoint blockade activates T cell immunity by reprogramming the STAT3 and STAT5 transcriptional pathways in dendritic cells, and STAT3 degradation is effective for treating tumours of multiple cancer types in mouse models.
