Southampton vs Manchester City predictions, odds and betting tips
Manchester City have found form at the perfect time. Pep Guardiola’s side are now the favourites to finish third and they might even be able to reel in Arsenal in the place above them. Southampton need one more point to move clear of Derby County’s all-time record low tally of 11. Can they spring a surprise by avoiding defeat by City? Manchester City to win both halves – 11/8 with Ladbrokes Manchester City -2 handicap – 11/8 with Sky Bet Kevin De Bruyne to score any time – 11/5 with bet365 Southampton vs Manchester City odds Find the latest match odds for Southampton vs Manchester City. All odds are provided by our best football betting sites. Odds are subject to change. Southampton vs Manchester City predictions Manchester City were in disarray earlier this season. If they were to win the FA Cup and finish as Premier League runners-up, that would be a pretty decent outcome all things considered. City face Crystal Palace in the FA Cup final next weekend, as they seek to lift the trophy for the third time under Guardiola. They also have Arsenal in their sights. The gap between the two teams is down to three points. Arsenal have a superior goal difference, but City’s run-in is kinder than the side currently in second. Of course, Guardiola and his players would have been disappointed with a runners-up placing last summer. Back then it looked like City were the team to beat in the title race once more. It has not turned out that way. Rodri’s injury is often held as the turning point and the Ballon d’Or holder has indeed been a big miss. But City’s issues ran deeper than the loss of one player. It became clear in late 2024 that an overhaul was needed. City started the job in January, bringing in Omar Marmoush, Abdukodir Khusanov, Nico Gonzalez and Vitor Reis. Kyle Walker bade farewell to the Etihad Stadium in the winter window and Kevin De Bruyne will do so soon. It would not be a surprise to see others move on in the summer, perhaps Bernardo Silva, Jack Grealish and Ilkay Gundogan. A rebuild awaits in the months ahead, while City will also take part in the expanded Club World Cup. Ordinarily that might be seen as a nuisance, but given Guardiola is in the middle of revamping his side, the tournament in the USA might actually help City to bed things in. Before then City have their eyes on silverware and Champions League qualification. For all the talk of Arsenal in second, Guardiola’s men are not yet guaranteed a top-five finish. They have a three-point buffer at present, which means two more wins would be enough to book a spot at Europe’s top table for 2025/26. Southampton are the ideal opponents for City’s final league game before the FA Cup final. Guardiola’s side head to St Mary’s as massive favourites after winning five games in a row in all competitions for the first time since October. Southampton vs Manchester City betting tips. 18+ GambleAware.org – Please play responsibly. Southampton vs Manchester City betting tips Manchester City are overwhelming favourites to get the better of Southampton this weekend. Manchester City to win both halves Southampton fans have had little to celebrate this season. A 2-0 defeat by 19th-placed Leicester City last weekend confirmed how bad the Saints have been. Stuck on 11 points, they only need one more to exceed Derby County’s record-low return of 11 from 2007/08. Free Bet Offers See all the best free bets and betting offers available over at our dedicated page See all free bets 18+ gambleaware.org. T&Cs apply But with games against Manchester City and Arsenal on the horizon, plus a trip to Everton as their last ever opponents at Goodison Park, Southampton could easily join Derby in the record books (their goal difference is minus 57 compared to the Rams’ minus 69). City are still not as imperious as they have been for most of the Guardiola era, but this should be a comfortable afternoon for them. Back Manchester City to win both halves at 11/8 with Ladbrokes Manchester City -2 handicap Southampton have had problems at both ends of the pitch this season, scoring the fewest goals and conceding the most. They have been defeated by three goals or more on seven occasions – and that could become eight on Saturday. Guardiola may have publicly played down the importance of catching Arsenal, but in private the City boss would surely love to overtake Mikel Arteta’s men. This is a golden opportunity for City to close the goal-difference gap by winning big on the south coast. Choose Manchester City with a -2 handicap at 11/8 with Sky Bet Kevin De Bruyne to score any time – 11/5 (bet365) “It was really good,” Guardiola said of De Bruyne’s match-winning display against Wolverhampton Wanderers last time out. “His contribution is massive… it’s not just titles and numbers, it’s affectio

Manchester City have found form at the perfect time. Pep Guardiola’s side are now the favourites to finish third and they might even be able to reel in Arsenal in the place above them.
Southampton need one more point to move clear of Derby County’s all-time record low tally of 11. Can they spring a surprise by avoiding defeat by City?
- Manchester City to win both halves – 11/8 with Ladbrokes
- Manchester City -2 handicap – 11/8 with Sky Bet
- Kevin De Bruyne to score any time – 11/5 with bet365
Southampton vs Manchester City odds
Find the latest match odds for Southampton vs Manchester City. All odds are provided by our best football betting sites. Odds are subject to change.
Southampton vs Manchester City predictions
Manchester City were in disarray earlier this season. If they were to win the FA Cup and finish as Premier League runners-up, that would be a pretty decent outcome all things considered.
City face Crystal Palace in the FA Cup final next weekend, as they seek to lift the trophy for the third time under Guardiola.
They also have Arsenal in their sights. The gap between the two teams is down to three points. Arsenal have a superior goal difference, but City’s run-in is kinder than the side currently in second.
Of course, Guardiola and his players would have been disappointed with a runners-up placing last summer. Back then it looked like City were the team to beat in the title race once more.
It has not turned out that way. Rodri’s injury is often held as the turning point and the Ballon d’Or holder has indeed been a big miss. But City’s issues ran deeper than the loss of one player. It became clear in late 2024 that an overhaul was needed.
City started the job in January, bringing in Omar Marmoush, Abdukodir Khusanov, Nico Gonzalez and Vitor Reis. Kyle Walker bade farewell to the Etihad Stadium in the winter window and Kevin De Bruyne will do so soon. It would not be a surprise to see others move on in the summer, perhaps Bernardo Silva, Jack Grealish and Ilkay Gundogan.
A rebuild awaits in the months ahead, while City will also take part in the expanded Club World Cup. Ordinarily that might be seen as a nuisance, but given Guardiola is in the middle of revamping his side, the tournament in the USA might actually help City to bed things in.
Before then City have their eyes on silverware and Champions League qualification. For all the talk of Arsenal in second, Guardiola’s men are not yet guaranteed a top-five finish.
They have a three-point buffer at present, which means two more wins would be enough to book a spot at Europe’s top table for 2025/26. Southampton are the ideal opponents for City’s final league game before the FA Cup final.
Guardiola’s side head to St Mary’s as massive favourites after winning five games in a row in all competitions for the first time since October.
Southampton vs Manchester City betting tips
Manchester City are overwhelming favourites to get the better of Southampton this weekend.
Manchester City to win both halves
Southampton fans have had little to celebrate this season. A 2-0 defeat by 19th-placed Leicester City last weekend confirmed how bad the Saints have been.
Stuck on 11 points, they only need one more to exceed Derby County’s record-low return of 11 from 2007/08.
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But with games against Manchester City and Arsenal on the horizon, plus a trip to Everton as their last ever opponents at Goodison Park, Southampton could easily join Derby in the record books (their goal difference is minus 57 compared to the Rams’ minus 69).
City are still not as imperious as they have been for most of the Guardiola era, but this should be a comfortable afternoon for them.
Back Manchester City to win both halves at 11/8 with Ladbrokes
Manchester City -2 handicap
Southampton have had problems at both ends of the pitch this season, scoring the fewest goals and conceding the most.
They have been defeated by three goals or more on seven occasions – and that could become eight on Saturday.
Guardiola may have publicly played down the importance of catching Arsenal, but in private the City boss would surely love to overtake Mikel Arteta’s men.
This is a golden opportunity for City to close the goal-difference gap by winning big on the south coast.
Choose Manchester City with a -2 handicap at 11/8 with Sky Bet
Kevin De Bruyne to score any time – 11/5 (bet365)
“It was really good,” Guardiola said of De Bruyne’s match-winning display against Wolverhampton Wanderers last time out.
“His contribution is massive… it’s not just titles and numbers, it’s affection and love and passion. All of us have been one decade here, helping us to win absolutely everything and still he’s here.”
He will not be for much longer. De Bruyne has admitted he would have liked to stay at the Eithad, but the powers that be had other ideas.
The Belgium international seems to have recaptured his best form since his impending exit was confirmed.
De Bruyne has scored two goals in his last four games and we like his chances of finding the net against Southampton.
Tip Kevin De Bruyne to score any time at 11/5 with bet365