Multi-zonal liver organoids from human pluripotent stem cells

Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08850-1Liver organoids derived from human induced pluripotent stem cells populations grown with ascorbate and bilirubin can be used to recapitulate differential zonal functions of human hepatocytes and for transplantation in animal models of liver dysfunction.

Apr 17, 2025 - 02:34
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Multi-zonal liver organoids from human pluripotent stem cells

Nature, Published online: 16 April 2025; doi:10.1038/s41586-025-08850-1Liver organoids derived from human induced pluripotent stem cells populations grown with ascorbate and bilirubin can be used to recapitulate differential zonal functions of human hepatocytes and for transplantation in animal models of liver dysfunction.