How morphogens steer early brain development by guiding stem cell gene activity

Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new Yale-led study shows that, early in development, molecular "traffic cops" known as morphogens regulate the activation of gene programs that initiate stem cells' differentiation into more specialized brain cells.

May 1, 2025 - 22:06
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Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new Yale-led study shows that, early in development, molecular "traffic cops" known as morphogens regulate the activation of gene programs that initiate stem cells' differentiation into more specialized brain cells.