Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium

Nature, Published online: 19 March 2025; doi:10.1038/s41586-025-08724-6Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result from continuous remodelling of cellular overlaps that maintain vessel integrity.

Mar 20, 2025 - 05:40
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Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium

Nature, Published online: 19 March 2025; doi:10.1038/s41586-025-08724-6Dynamic cytoskeletal regulation of lymphatic endothelial cell shape, induced by isotropic stretch and crucial for dermal lymphatic capillary function, is identified and found to result from continuous remodelling of cellular overlaps that maintain vessel integrity.