Duke vs Houston: Betting odds, predictions, pick & promos

For the first time since 2008, the Final Four features all No. 1 seeds, and according to advanced analytics, the second of the two matchups features the best offense and defense.  The Blue Devils are the No. 1 seed from the East, and the Cougars are the No. 1 seed from the Midwest.  This game will occur at 8:49 p.m. EDT on Saturday, April 5. Find the preview for the matchup below, including pick, promos to bet on the game and much more. Best betting promos for Duke vs Houston Find the best promos from the best sportsbooks for the NCAA Finals. Learn more about betting on the tournament in the NCAA Finals betting and strategy guide. Duke (1) vs Houston (1) preview No. 1 Duke took on No. 2 Alabama in the Elite Eight. This was expected to be a bit of a shootout with how well Alabama’s offense has played this season, but they went cold and lost to Duke 85-65. The Blue Devils shot 53.6% from the field and 46.2% from 3-point range. Alabama shot just 35.4% from the field and 25% from 3-point range. Blue Devils players Cooper Flagg, Tyrese Proctor, Khaman Maluach, and Kon Knueppel each had double-digit points.  No. 1 Houston took on No. 2 Tennessee. Alabama and Duke was expected to be a shootout and this one was projected to be a defensive showdown. However, Tennessee didn’t live up to it. They were outscored 34-15 in the first half. Tennessee shot just 28.8% from the field and 17.2% from 3-point range. Meanwhile, Houston shot 42.4% from the field and 36% from beyond the arc. Houston’s LJ Cryer had 17 points, seven rebounds, and four assists. Duke vs Houston odds Below are the odds for this matchup, courtesy of Fanduel Sportsbook.  Spread: Houston (+4.5, -105); Duke (-4.5, -115).  Moneyline: Houston (+172) Duke (-210).  Total: Over 136.5 (-110); Under 136.5 (-110) Get ready for the game with Fanduel’s amazing promo. Read more about the Fanduel Bet $5 Get $200 in Bonus Bets, and find out how you can claim your bonus bets. . Duke vs Houston analysis According to KenPom, Duke averages 130.1 points per 100 possessions (first) and allows just 90.5 points per 100 possessions (fourth). Conversely, Houston averages 123.9 points per 100 possessions (10th) and allows just 87.4 points per 100 possessions (first).  So, we have two teams that are No. 1 in each category, but Duke is also quite good defensively, and we’ve seen throughout this tournament, holding three of four teams to 66 points or less.  Duke has also been highly efficient. They’ve shot over 60% from the field in two games and 50% or higher in all four tournament matchups.  Duke allowed 93 points to an Arizona team that’s 12th in adjusted offensive efficiency, but they also sunk 46.2% of their 3-point shots when they’re typically just a 33.8% 3-point shooting team Duke vs Houston pick I’m going with Duke in this one. Houston put up just 62 against Purdue and 69 against Tennessee. Meanwhile, Duke has scored no less than 85 in any game.  They have too many star players. Houston has a great 3-point shooter in LJ Cryer, but Duke holds opponents to a mere 30.8% shooting percentage on 3-point shots.  Not only does Duke have a fantastic offense, but their defense is right up there with Houston.  I think Duke wins by perhaps double digits and easily covers this 4.5 number. Duke -4.5 (-115) at FanDuel Duke vs Houston Game Info Who: Duke (1) vs Houston (1) Date: Saturday, April 5 Time: 8:49 p.m. ET  Location: Alamodome in San Antonio, TX Where to watch: CBS About the author Richard Janvrin Richard Janvrin brings nearly a decade of experience covering sports, sports betting, and everything iGaming. Richard received his bachelor’s degree in Journalism/English from the University of New Hampshire. Throughout his career, Richard has written for sites like Bleacher Report, Forbes, The Game Day, WSN, Gambling.com, and many more. Find him on Twitter: @RichardJanvrin Commercial content notice: Taking one of the sportsbooks offers featured in this article may result in a payment to talkSPORT. 21+. T&Cs apply. Gambling Problem? Call 1-800-Gambler Responsible gambling  Remember to gamble responsiblyA responsible gambler is someone who: Establishes time and monetary limits before playingOnly gambles with money they can afford to loseNever chase their lossesDoesn’t gamble if they’re upset, angry, or depressedNational Council on Problem Gambling – https://www.ncpgambling.org/Gamble Aware – www.begambleaware.org For help with a gambling problem, call the National Gambling Helpline on 1-800-522-4700 or go to ncpgambling.org/chat Most read in Sportsbooks US Auburn vs Florida: Betting odds, predictions, pick & promos

Apr 5, 2025 - 22:59
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Duke vs Houston: Betting odds, predictions, pick & promos

For the first time since 2008, the Final Four features all No. 1 seeds, and according to advanced analytics, the second of the two matchups features the best offense and defense. 

The Blue Devils are the No. 1 seed from the East, and the Cougars are the No. 1 seed from the Midwest. 

This game will occur at 8:49 p.m. EDT on Saturday, April 5. Find the preview for the matchup below, including pick, promos to bet on the game and much more.

Best betting promos for Duke vs Houston

Find the best promos from the best sportsbooks for the NCAA Finals. Learn more about betting on the tournament in the NCAA Finals betting and strategy guide.

Duke (1) vs Houston (1) preview

No. 1 Duke took on No. 2 Alabama in the Elite Eight. This was expected to be a bit of a shootout with how well Alabama’s offense has played this season, but they went cold and lost to Duke 85-65.

The Blue Devils shot 53.6% from the field and 46.2% from 3-point range. Alabama shot just 35.4% from the field and 25% from 3-point range. Blue Devils players Cooper Flagg, Tyrese Proctor, Khaman Maluach, and Kon Knueppel each had double-digit points. 

No. 1 Houston took on No. 2 Tennessee. Alabama and Duke was expected to be a shootout and this one was projected to be a defensive showdown. However, Tennessee didn’t live up to it.

They were outscored 34-15 in the first half. Tennessee shot just 28.8% from the field and 17.2% from 3-point range.

Meanwhile, Houston shot 42.4% from the field and 36% from beyond the arc. Houston’s LJ Cryer had 17 points, seven rebounds, and four assists.

Duke vs Houston odds

Below are the odds for this matchup, courtesy of Fanduel Sportsbook

  • Spread: Houston (+4.5, -105); Duke (-4.5, -115). 
  • Moneyline: Houston (+172) Duke (-210). 
  • Total: Over 136.5 (-110); Under 136.5 (-110)

Get ready for the game with Fanduel’s amazing promo. Read more about the Fanduel Bet $5 Get $200 in Bonus Bets, and find out how you can claim your bonus bets. .

Duke vs Houston analysis

According to KenPom, Duke averages 130.1 points per 100 possessions (first) and allows just 90.5 points per 100 possessions (fourth). Conversely, Houston averages 123.9 points per 100 possessions (10th) and allows just 87.4 points per 100 possessions (first). 

So, we have two teams that are No. 1 in each category, but Duke is also quite good defensively, and we’ve seen throughout this tournament, holding three of four teams to 66 points or less. 

Duke has also been highly efficient. They’ve shot over 60% from the field in two games and 50% or higher in all four tournament matchups. 

Duke allowed 93 points to an Arizona team that’s 12th in adjusted offensive efficiency, but they also sunk 46.2% of their 3-point shots when they’re typically just a 33.8% 3-point shooting team

Duke vs Houston pick

I’m going with Duke in this one. Houston put up just 62 against Purdue and 69 against Tennessee. Meanwhile, Duke has scored no less than 85 in any game. 

They have too many star players. Houston has a great 3-point shooter in LJ Cryer, but Duke holds opponents to a mere 30.8% shooting percentage on 3-point shots. 

Not only does Duke have a fantastic offense, but their defense is right up there with Houston. 

I think Duke wins by perhaps double digits and easily covers this 4.5 number.

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