A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome
Nature, Published online: 26 March 2025; doi:10.1038/s41586-025-08723-7A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common resistance mechanisms and shows no toxicity towards human cells.
Nature, Published online: 26 March 2025; doi:10.1038/s41586-025-08723-7A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common resistance mechanisms and shows no toxicity towards human cells.
